Doc: Everything You Need to Know About the Fox Medical Drama
The Fox medical drama Doc quickly became one of 2025’s breakout series. Developed by Barbie Kligman, Doc premiered on January 7, 2025, delivering an emotional twist on the traditional hospital drama format.
Inspired by the Italian series Doc – Nelle tue mani, the show blends medical intensity with deeply personal storytelling. With a strong ensemble cast, high-stakes cases, and layered character arcs, Doc has secured a 22-episode second season and continues to expand its audience.
Here’s everything you need to know about Doc, including the cast, storyline, filming locations, and casting directors behind the series.
What Is Doc About?
At the center of Doc is Dr. Amy Larsen, the Chief of Internal Medicine at Minneapolis’s fictional Westside Hospital.
After surviving a serious car accident, Amy suffers a traumatic brain injury that erases the last eight years of her life. She cannot remember:
- Her divorce
- The death of her son
- Professional conflicts with colleagues
- Romantic relationships
- Critical career decisions
Forced to retake her board exams and rebuild her credibility, Amy must confront a version of herself described as brilliant but emotionally distant.
Doc explores identity, redemption, and whether someone deserves a second chance when they no longer remember their past mistakes.
Is Doc Based on a True Story?
Yes — indirectly.
Doc is adapted from the Italian series Doc – Nelle tue mani, which was inspired by the real-life story of Dr. Pierdante Piccioni. After a 2013 car accident, he lost 12 years of his memory.
While the Fox adaptation reimagines the setting and characters, the emotional premise remains rooted in that extraordinary real-life experience.
Doc Cast: Who Stars in the Series?
The cast of Doc features a strong lineup of established actors and emerging talent.
Main Cast
- Molly Parker as Dr. Amy Larsen
- Omar Metwally as Dr. Michael Hamda
- Jon Ecker as Dr. Jake Heller
- Amirah Vann as Dr. Gina Walker
- Anya Banerjee as Dr. Sonya Maitra
- Patrick Walker as Dr. TJ Coleman
- Charlotte Fountain-Jardim as Katie Hamda
- Felicity Huffman (Season 2) as Dr. Joan Ridley
Recurring and guest stars include Scott Wolf, Sarah Allen, Brian Tee, and others.
Doc Season 1 Recap
Season 1 follows Amy’s journey to reclaim her career while uncovering truths about her past. Major developments include:
- Re-taking her medical board exams
- Investigating a possible medical cover-up
- Repairing her relationship with her daughter
- Complicated romantic tensions
- Leadership shakeups at Westside Hospital
Season 1 ran for 10 episodes from January 7 to March 18, 2025.
Doc Season 2: Bigger Stakes and New Challenges
Fox renewed Doc in February 2025 for a 22-episode second season — the first Fox drama to receive a full 22-episode order since The Resident.
Season 2 premiered on September 14, 2025, and escalates the drama with:
- A hostage situation inside the hospital
- A transplant program suspension
- FBI and medical board investigations
- TMS therapy to recover Amy’s memories
- A leadership battle for Chief Resident
- Sabotage involving AI deepfakes
The expanded season opens the door for additional guest stars, recurring characters, and supporting roles.
Who Are the Casting Directors for Doc?
Casting plays a vital role in shaping the emotional authenticity of Doc. From lead roles to guest patients and hospital staff, casting directors ensure each performance supports the show’s layered storytelling.
One of the casting teams associated with the project is TMH Management, a Toronto-based talent agency known for representing diverse performers in film and television.
TMH Management has been serving the entertainment industry since 1998 and is recognized for its professional and experienced approach. Based in Toronto — where Doc is filmed — the agency works closely with productions across Canada’s thriving television industry.
As Doc continues its second season with a larger episode order, casting directors and talent agencies like TMH Management help connect productions with:
- Series regulars
- Recurring roles
- Guest stars
- Day players
- Background performers
With Toronto serving as a major production hub, local casting partnerships are key to building the world of Doc.
Where Is Doc Filmed?
Production for Doc began in March 2024.
Filming locations include:
- Toronto, Ontario
- Oakville, Ontario
Season 2 production began in June 2025 and is scheduled to continue through April 2026.
The series is produced by:
- 3 Arts Entertainment
- Fox Entertainment
- Sony Pictures Television
Ratings and Reception
Doc has received mixed critical reviews.
- Rotten Tomatoes: 44% approval rating
- Metacritic: 58/100 (mixed or average reviews)
Despite divided critics, audience interest remains strong, especially following Season 2’s expanded episode order.
Where to Watch Doc
- Airs on Fox in the United States
- Streams on Hulu
- Airs on Global and streams on StackTV in Canada
- Available on AXN Asia in Southeast Asia
- Streaming on Disney+ in Latin America
FOX’s ‘DOC’ Casting Call for Bistro Patrons
ACTRA Background Roles for Documentary Bistro & Hospital Scenes
Job Description
A documentary-style production is now casting ACTRA Apprentice and Full members for multiple paid background roles filming in Oakville. This casting call is seeking performers to portray upscale casual bistro patrons, attractive servers, shoppers, and non-regular hospital nurses for a Florida-set scene.
Production is looking for diverse, authentic talent in their 30s to 60s who can naturally blend into realistic restaurant and hospital environments. Please note: no repeats from previous specified filming dates and no performers who regularly portray hospital staff on this production.
Shuttle transportation from Kipling Subway is available for those who require it.
Job Responsibilities
- Portray upscale casual bistro patrons in restaurant scenes
- Perform as servers interacting naturally in a dining environment
- Appear as shoppers in background retail moments
- Portray non-regular nurses in hospital scenes set in Florida
- Follow direction from assistant directors and production team
- Maintain continuity and professionalism on set
Requirements
- ACTRA Apprentice or Full members only
- Age range primarily 30s–60s (depending on role)
- Diverse talent encouraged, including:
- 1 Black female nurse
- 1 Black male nurse
- 1 Latina female nurse
- No repeats from previously specified shoot dates
- Must not regularly portray hospital staff on this production
- Available to work in Oakville
- Submit full measurements and union status as requested
- Provide recent photo (and hand photo if submitting as hand double)
Compensation
- Paid ACTRA background rates
- Shuttle available from Kipling Subway
- Professional credit on documentary production
- Opportunity to work in multiple realistic setting scenes
“DOC” Casting Call for Replacement Role
Non-Union Talent for Doc Replacement Role
Job Description
An urgent casting call is now seeking two non-union actors who can work in Oakville for a documentary-style production. Casting directors are specifically looking for fresh faces who have not previously appeared on this project.
This opportunity requires same-day or immediate availability, with talent able to arrive in Oakville before 2:30 PM. Actors must be professional, reliable, and ready to step into a replacement role for an ongoing documentary shoot.
If you are a non-union performer with flexible availability and can work locally in Oakville, this is a fast-moving casting opportunity.
Job Responsibilities
- Portray a replacement role in a documentary production
- Arrive on set in Oakville before 2:30 PM
- Follow direction from the production team
- Maintain professionalism during filming
- Provide accurate measurements and required submission details
Requirements
- Non-union talent only
- Must not have previously worked on this documentary
- Must be available immediately
- Able to work locally in Oakville
- Submit full name, current photo (including hands if applying for hand double), phone number, email address, and union status
- Provide measurements:
- Women: height, weight, bust, waist, hips, dress size, shoe size
- Men: height, weight, neck, jacket, waist, inseam, shoe size
Compensation
- Paid non-union documentary role
- On-set production experience
- Opportunity for future casting consideration
Ready to Land Your Next TV Role?
With major productions like Doc filming in Toronto and across North America, opportunities are constantly opening for actors, background performers, and industry professionals.
If you’re ready to apply for television casting calls and discover new roles, explore active opportunities now on Project Casting.
👉 Visit www.projectcasting.com to browse casting calls and apply today.
